BDBM68189 5-(6-methyl-2-imidazo[1,2-a]pyridinyl)-3-phenylisoxazole::5-(6-methylimidazo[1,2-a]pyridin-2-yl)-3-phenyl-1,2-oxazole::5-(6-methylimidazo[1,2-a]pyridin-2-yl)-3-phenyl-isoxazole::6-methyl-2-(3-phenyl-5-isoxazolyl)imidazo[1,2-a]pyridine::MLS000860564::SMR000458648::cid_2813808

SMILES: Cc1ccc2nc(cn2c1)-c1cc(no1)-c1ccccc1

InChI Key: InChIKey=FCTSBNQGQACUQF-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 68189   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA damage-inducible transcript 3 protein (Mus musculus)	BDBM68189 (5-(6-methyl-2-imidazo[1,2-a]pyridinyl)-3-phenyliso...) Show SMILES Cc1ccc2nc(cn2c1)-c1cc(no1)-c1ccccc1 Show InChI InChI=1S/C17H13N3O/c1-12-7-8-17-18-15(11-20(17)10-12)16-9-14(19-21-16)13-5-3-2-4-6-13/h2-11H,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2PC30VZ
					More data for this Ligand-Target Pair
nuclear receptor corepressor 2 isoform 2 (Homo sapiens (Human))	BDBM68189 (5-(6-methyl-2-imidazo[1,2-a]pyridinyl)-3-phenyliso...) Show SMILES Cc1ccc2nc(cn2c1)-c1cc(no1)-c1ccccc1 Show InChI InChI=1S/C17H13N3O/c1-12-7-8-17-18-15(11-20(17)10-12)16-9-14(19-21-16)13-5-3-2-4-6-13/h2-11H,1H3	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>3.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q26T0K34
					More data for this Ligand-Target Pair
photoreceptor-specific nuclear receptor (Homo sapiens (Human))	BDBM68189 (5-(6-methyl-2-imidazo[1,2-a]pyridinyl)-3-phenyliso...) Show SMILES Cc1ccc2nc(cn2c1)-c1cc(no1)-c1ccccc1 Show InChI InChI=1S/C17H13N3O/c1-12-7-8-17-18-15(11-20(17)10-12)16-9-14(19-21-16)13-5-3-2-4-6-13/h2-11H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>3.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2BK19S0
					More data for this Ligand-Target Pair
HIV-1 B HXB2-LAI-IIIB-BRU (Human immunodeficiency virus type 1 group M subtyp...)	BDBM68189 (5-(6-methyl-2-imidazo[1,2-a]pyridinyl)-3-phenyliso...) Show SMILES Cc1ccc2nc(cn2c1)-c1cc(no1)-c1ccccc1 Show InChI InChI=1S/C17H13N3O/c1-12-7-8-17-18-15(11-20(17)10-12)16-9-14(19-21-16)13-5-3-2-4-6-13/h2-11H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q29W0D3P
					More data for this Ligand-Target Pair
XBP1 (Homo sapiens (Human))	BDBM68189 (5-(6-methyl-2-imidazo[1,2-a]pyridinyl)-3-phenyliso...) Show SMILES Cc1ccc2nc(cn2c1)-c1cc(no1)-c1ccccc1 Show InChI InChI=1S/C17H13N3O/c1-12-7-8-17-18-15(11-20(17)10-12)16-9-14(19-21-16)13-5-3-2-4-6-13/h2-11H,1H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2NK3CGB
					More data for this Ligand-Target Pair
HIV-1 B HXB2-LAI-IIIB-BRU (Human immunodeficiency virus type 1 group M subtyp...)	BDBM68189 (5-(6-methyl-2-imidazo[1,2-a]pyridinyl)-3-phenyliso...) Show SMILES Cc1ccc2nc(cn2c1)-c1cc(no1)-c1ccccc1 Show InChI InChI=1S/C17H13N3O/c1-12-7-8-17-18-15(11-20(17)10-12)16-9-14(19-21-16)13-5-3-2-4-6-13/h2-11H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2KD1WJB
					More data for this Ligand-Target Pair
HIV-1 B HXB2-LAI-IIIB-BRU (Human immunodeficiency virus type 1 group M subtyp...)	BDBM68189 (5-(6-methyl-2-imidazo[1,2-a]pyridinyl)-3-phenyliso...) Show SMILES Cc1ccc2nc(cn2c1)-c1cc(no1)-c1ccccc1 Show InChI InChI=1S/C17H13N3O/c1-12-7-8-17-18-15(11-20(17)10-12)16-9-14(19-21-16)13-5-3-2-4-6-13/h2-11H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2FN14T0
					More data for this Ligand-Target Pair
DNA damage-inducible transcript 3 protein (Mus musculus)	BDBM68189 (5-(6-methyl-2-imidazo[1,2-a]pyridinyl)-3-phenyliso...) Show SMILES Cc1ccc2nc(cn2c1)-c1cc(no1)-c1ccccc1 Show InChI InChI=1S/C17H13N3O/c1-12-7-8-17-18-15(11-20(17)10-12)16-9-14(19-21-16)13-5-3-2-4-6-13/h2-11H,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q28C9TQN
					More data for this Ligand-Target Pair