BDBM81337 tBuGTP (2b)

SMILES: CC(C)(C)c1nc2c(nc(N)[nH]c2=O)n1[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)C(O)C1O

InChI Key: InChIKey=SZVUTFJCZJHZKL-VTFQDDHLSA-K

Data: 2 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 81337   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
FtsZ (Aquifex aeolicus)	BDBM81337 (tBuGTP (2b)) Show SMILES CC(C)(C)c1nc2c(nc(N)[nH]c2=O)n1[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)C(O)C1O |r| Show InChI InChI=1S/C14H24N5O14P3/c1-14(2,3)12-16-6-9(17-13(15)18-10(6)22)19(12)11-8(21)7(20)5(31-11)4-30-35(26,27)33-36(28,29)32-34(23,24)25/h5,7-8,11,20-21H,4H2,1-3H3,(H,26,27)(H,28,29)(H2,23,24,25)(H3,15,17,18,22)/p-3/t5-,7?,8?,11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.15E+4	n/a	n/a	n/a	n/a	7.5	n/a
University of Amsterdam					Assay Description The binding affinities to FtsZ were determined by a fluorescent coupled assay for phosphate relase. In this GTPase studies, phosphate liberated durin...				Chem Biol 15: 189-99 (2008) Article DOI: 10.1016/j.chembiol.2007.12.013 BindingDB Entry DOI: 10.7270/Q2P849CR
					More data for this Ligand-Target Pair
FtsZ (Aquifex aeolicus)	BDBM81337 (tBuGTP (2b)) Show SMILES CC(C)(C)c1nc2c(nc(N)[nH]c2=O)n1[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)C(O)C1O |r| Show InChI InChI=1S/C14H24N5O14P3/c1-14(2,3)12-16-6-9(17-13(15)18-10(6)22)19(12)11-8(21)7(20)5(31-11)4-30-35(26,27)33-36(28,29)32-34(23,24)25/h5,7-8,11,20-21H,4H2,1-3H3,(H,26,27)(H,28,29)(H2,23,24,25)(H3,15,17,18,22)/p-3/t5-,7?,8?,11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+4	91	n/a	n/a	n/a	7.5	n/a
University of Amsterdam					Assay Description The binding affinities to FtsZ were determined by a fluorescent competition assay with 2'/3'-O-(N-methyl-anthraniloyl)-guanosine-5'-triph...				Chem Biol 15: 189-99 (2008) Article DOI: 10.1016/j.chembiol.2007.12.013 BindingDB Entry DOI: 10.7270/Q2P849CR
					More data for this Ligand-Target Pair