BDBM81702 LpxC Inhibitor, L3
SMILES: Cc1cc(ccc1F)C1=N[C@H](CO1)C(=O)NO
InChI Key: InChIKey=REJGWQXKFQPAHU-SECBINFHSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UDP-3-O-acyl-GlcNAc deacetylase (LpxC) (Pseudomonas aeruginosa) | BDBM81702 (LpxC Inhibitor, L3) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Pharmaceutical Education and Research | Assay Description The LpxC inhibitors were used as the reference for development of flexible alignment-based pharamcophore, pharamcophore mapping study. | Chem Biol Drug Des 71: 45-56 (2008) Article DOI: 10.1111/j.1747-0285.2007.00608.x BindingDB Entry DOI: 10.7270/Q2K64GJF | |||||||||||
More data for this Ligand-Target Pair |