BDBM81702 LpxC Inhibitor, L3

SMILES: Cc1cc(ccc1F)C1=N[C@H](CO1)C(=O)NO

InChI Key: InChIKey=REJGWQXKFQPAHU-SECBINFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 81702   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
UDP-3-O-acyl-GlcNAc deacetylase (LpxC) (Pseudomonas aeruginosa)	BDBM81702 (LpxC Inhibitor, L3) Show SMILES Cc1cc(ccc1F)C1=N[C@H](CO1)C(=O)NO |r,t:9| Show InChI InChI=1S/C11H11FN2O3/c1-6-4-7(2-3-8(6)12)11-13-9(5-17-11)10(15)14-16/h2-4,9,16H,5H2,1H3,(H,14,15)/t9-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research					Assay Description The LpxC inhibitors were used as the reference for development of flexible alignment-based pharamcophore, pharamcophore mapping study.				Chem Biol Drug Des 71: 45-56 (2008) Article DOI: 10.1111/j.1747-0285.2007.00608.x BindingDB Entry DOI: 10.7270/Q2K64GJF
					More data for this Ligand-Target Pair