BDBM92475 Compound I
SMILES: NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCc4ccccc34)ncnc12
InChI Key: InChIKey=PGAMXUGSHMQFKD-XTMLTMLVSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ubiquitin activating enzyme (UAE) (Homo sapiens (Human)) | BDBM92475 (Compound I) | MMDB Reactome pathway B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Inc. | Assay Description Inhibition assay using ubiquitin. | J Biol Chem 286: 40867-77 (2011) Article DOI: 10.1074/jbc.M111.279984 BindingDB Entry DOI: 10.7270/Q26W98P4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ubiquitin activating enzyme (UAE) (Homo sapiens (Human)) | BDBM92475 (Compound I) | MMDB Reactome pathway B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Inc. | Assay Description Inhibition assay using ubiquitin. | J Biol Chem 286: 40867-77 (2011) Article DOI: 10.1074/jbc.M111.279984 BindingDB Entry DOI: 10.7270/Q26W98P4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ubiquitin activating enzyme (UAE) (Homo sapiens (Human)) | BDBM92475 (Compound I) | MMDB Reactome pathway B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 90.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Inc. | Assay Description Inhibition assay using ubiquitin. | J Biol Chem 286: 40867-77 (2011) Article DOI: 10.1074/jbc.M111.279984 BindingDB Entry DOI: 10.7270/Q26W98P4 | |||||||||||
More data for this Ligand-Target Pair |