BDBM26651 1-benzyl-5-[(4-ethoxyphenyl)methylidene]imidazolidine-2,4-dione::5-Arylidene-3-benzylhydantoin, 28c::E/Z=4/1

SMILES: CCOc1ccc(C=C2N(Cc3ccccc3)C(=O)NC2=O)cc1

InChI Key: InChIKey=FCWWXAGQMABXRA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26651   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM26651 (1-benzyl-5-[(4-ethoxyphenyl)methylidene]imidazolid...) Show SMILES CCOc1ccc(C=C2N(Cc3ccccc3)C(=O)NC2=O)cc1 Show InChI InChI=1S/C19H18N2O3/c1-2-24-16-10-8-14(9-11-16)12-17-18(22)20-19(23)21(17)13-15-6-4-3-5-7-15/h3-12H,2,13H2,1H3,(H,20,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina					Assay Description The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...				J Med Chem 52: 74-86 (2009) Article DOI: 10.1021/jm800937p BindingDB Entry DOI: 10.7270/Q2S180SF
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM26651 (1-benzyl-5-[(4-ethoxyphenyl)methylidene]imidazolid...) Show SMILES CCOc1ccc(C=C2N(Cc3ccccc3)C(=O)NC2=O)cc1 Show InChI InChI=1S/C19H18N2O3/c1-2-24-16-10-8-14(9-11-16)12-17-18(22)20-19(23)21(17)13-15-6-4-3-5-7-15/h3-12H,2,13H2,1H3,(H,20,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina					Assay Description The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...				J Med Chem 52: 74-86 (2009) Article DOI: 10.1021/jm800937p BindingDB Entry DOI: 10.7270/Q2S180SF
					More data for this Ligand-Target Pair