BindingDB PrimarySearch

BDBM50297394 CHEMBL4171115

SMILES: COc1cc2c(Oc3ccc(NC(=O)NN4C(SCC4=O)c4c(F)cccc4F)c(F)c3)ccnc2cc1OCCCN1CCCC1

InChI Key: InChIKey=FQIRYXKZWMEKES-UHFFFAOYSA-N

Data: 9 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50297394
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50297394 (CHEMBL4171115) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0210	n/a	n/a	n/a	n/a	n/a	n/a
Zhuhai Campus of Zunyi Medical University Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA				Eur J Med Chem 146: 368-380 (2018) Article DOI: 10.1016/j.ejmech.2018.01.061 BindingDB Entry DOI: 10.7270/Q2BP059Q
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50297394 (CHEMBL4171115) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0290	n/a	n/a	n/a	n/a	n/a	n/a
Zhuhai Campus of Zunyi Medical University Curated by ChEMBL					Assay Description Inhibition of [125I]VCAM-Ig binding to VLA-4 of Jurkat cells in the presence of [Ca2+]				Eur J Med Chem 146: 368-380 (2018) Article DOI: 10.1016/j.ejmech.2018.01.061 BindingDB Entry DOI: 10.7270/Q2BP059Q
					More data for this Ligand-Target Pair
Macrophage-stimulating protein receptor (Homo sapiens (Human))	BDBM50297394 (CHEMBL4171115) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.00310	n/a	n/a	n/a	n/a	n/a	n/a
Zhuhai Campus of Zunyi Medical University Curated by ChEMBL					Assay Description Inhibition of Ron (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA				Eur J Med Chem 146: 368-380 (2018) Article DOI: 10.1016/j.ejmech.2018.01.061 BindingDB Entry DOI: 10.7270/Q2BP059Q
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50297394 (CHEMBL4171115) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0210	n/a	n/a	n/a	n/a	n/a	n/a
Zhuhai Campus of Zunyi Medical University Curated by ChEMBL					Assay Description Inhibition of KDR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA				Eur J Med Chem 146: 368-380 (2018) Article DOI: 10.1016/j.ejmech.2018.01.061 BindingDB Entry DOI: 10.7270/Q2BP059Q
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50297394 (CHEMBL4171115) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0610	n/a	n/a	n/a	n/a	n/a	n/a
Zhuhai Campus of Zunyi Medical University Curated by ChEMBL					Assay Description Inhibition of Src (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA				Eur J Med Chem 146: 368-380 (2018) Article DOI: 10.1016/j.ejmech.2018.01.061 BindingDB Entry DOI: 10.7270/Q2BP059Q
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50297394 (CHEMBL4171115) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0620	n/a	n/a	n/a	n/a	n/a	n/a
Zhuhai Campus of Zunyi Medical University Curated by ChEMBL					Assay Description Inhibition of AXL (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA				Eur J Med Chem 146: 368-380 (2018) Article DOI: 10.1016/j.ejmech.2018.01.061 BindingDB Entry DOI: 10.7270/Q2BP059Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50297394 (CHEMBL4171115) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.812	n/a	n/a	n/a	n/a	n/a	n/a
Zhuhai Campus of Zunyi Medical University Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA				Eur J Med Chem 146: 368-380 (2018) Article DOI: 10.1016/j.ejmech.2018.01.061 BindingDB Entry DOI: 10.7270/Q2BP059Q
					More data for this Ligand-Target Pair
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50297394 (CHEMBL4171115) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Zhuhai Campus of Zunyi Medical University Curated by ChEMBL					Assay Description Inhibition of IGF1R (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA				Eur J Med Chem 146: 368-380 (2018) Article DOI: 10.1016/j.ejmech.2018.01.061 BindingDB Entry DOI: 10.7270/Q2BP059Q
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50297394 (CHEMBL4171115) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.152	n/a	n/a	n/a	n/a	n/a	n/a
Zhuhai Campus of Zunyi Medical University Curated by ChEMBL					Assay Description Inhibition of RET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA				Eur J Med Chem 146: 368-380 (2018) Article DOI: 10.1016/j.ejmech.2018.01.061 BindingDB Entry DOI: 10.7270/Q2BP059Q
					More data for this Ligand-Target Pair