BindingDB PrimarySearch

BDBM50021398 CHEBI:18088::FORMONONETIN::NSC-93360

SMILES: COc1ccc(cc1)-c1coc2cc(O)ccc2c1=O

InChI Key: InChIKey=HKQYGTCOTHHOMP-UHFFFAOYSA-N

Data: 1 KI 14 IC50 1 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50021398
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cytochrome P450 1B1 (Homo sapiens (Human))	BDBM50021398 (CHEBI:18088 \| FORMONONETIN \| NSC-93360) Show SMILES COc1ccc(cc1)-c1coc2cc(O)ccc2c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Endocrinology and Nephrology Unit, CHU de Qu�bec - Research Center, Qu�bec, Qu�bec, Canada; Department of Molecular Medicine, Faculty of Medicine, Universit� Laval, Curated by ChEMBL					Assay Description Inhibition of CYP1B1 in human liver microsomes coexpressing recombinant human cytochrome P450 oxidoreductase using 7-ethoxyresorufin as substrate aft...				Eur J Med Chem 135: 296-306 (2017) Article DOI: 10.1016/j.ejmech.2017.04.042 BindingDB Entry DOI: 10.7270/Q26Q20QW
					More data for this Ligand-Target Pair
Cytochrome P450 1A (Homo sapiens (Human))	BDBM50021398 (CHEBI:18088 \| FORMONONETIN \| NSC-93360) Show SMILES COc1ccc(cc1)-c1coc2cc(O)ccc2c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Inhibition of CYP1A1 by EROD assay				J Med Chem 49: 3973-81 (2006) Article DOI: 10.1021/jm060359j BindingDB Entry DOI: 10.7270/Q27H1NBP
University of Nottingham Curated by ChEMBL					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus)	BDBM50021398 (CHEBI:18088 \| FORMONONETIN \| NSC-93360) Show SMILES COc1ccc(cc1)-c1coc2cc(O)ccc2c1=O Show InChI	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of Influenza A PR/8/34 H1N1 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assay				Bioorg Med Chem 16: 7141-7 (2008) Article DOI: 10.1016/j.bmc.2008.06.049 BindingDB Entry DOI: 10.7270/Q2R2145D
Peking Union Medical College Curated by ChEMBL					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus)	BDBM50021398 (CHEBI:18088 \| FORMONONETIN \| NSC-93360) Show SMILES COc1ccc(cc1)-c1coc2cc(O)ccc2c1=O Show InChI	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of Influenza A Jinan/15/90 H3N2 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assay				Bioorg Med Chem 16: 7141-7 (2008) Article DOI: 10.1016/j.bmc.2008.06.049 BindingDB Entry DOI: 10.7270/Q2R2145D
Peking Union Medical College Curated by ChEMBL					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus)	BDBM50021398 (CHEBI:18088 \| FORMONONETIN \| NSC-93360) Show SMILES COc1ccc(cc1)-c1coc2cc(O)ccc2c1=O Show InChI	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of Influenza A Jiangsu/10/2003 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assay				Bioorg Med Chem 16: 7141-7 (2008) Article DOI: 10.1016/j.bmc.2008.06.049 BindingDB Entry DOI: 10.7270/Q2R2145D
Peking Union Medical College Curated by ChEMBL					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus)	BDBM50021398 (CHEBI:18088 \| FORMONONETIN \| NSC-93360) Show SMILES COc1ccc(cc1)-c1coc2cc(O)ccc2c1=O Show InChI	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Inhibition of oseltamivir-resistant Influenza A virus H1N1 B/55/08 neuraminidase by chemiluminescence based assay				J Nat Prod 77: 563-70 (2014) Article DOI: 10.1021/np400817j BindingDB Entry DOI: 10.7270/Q23J3GZJ
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome subunit beta type-1/beta type-5 (Homo sapiens (Human))	BDBM50021398 (CHEBI:18088 \| FORMONONETIN \| NSC-93360) Show SMILES COc1ccc(cc1)-c1coc2cc(O)ccc2c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Agricultural and Food Biotechnology Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of purified human erythrocyte 20S proteasome assessed as decrease in AMC hydrolysis using Suc-LLVY-AMC as su...				Eur J Med Chem 167: 291-311 (2019) Article DOI: 10.1016/j.ejmech.2019.01.044
					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus)	BDBM50021398 (CHEBI:18088 \| FORMONONETIN \| NSC-93360) Show SMILES COc1ccc(cc1)-c1coc2cc(O)ccc2c1=O Show InChI	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Inhibition of Influenza A virus (A/Puerto Rico/8/1934(H1N1)) neuraminidase by chemiluminescence based assay				J Nat Prod 77: 563-70 (2014) Article DOI: 10.1021/np400817j BindingDB Entry DOI: 10.7270/Q23J3GZJ
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus)	BDBM50021398 (CHEBI:18088 \| FORMONONETIN \| NSC-93360) Show SMILES COc1ccc(cc1)-c1coc2cc(O)ccc2c1=O Show InChI	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Inhibition of Influenza A virus (A/Hong Kong/1/1968(H3N2)) neuraminidase by chemiluminescence based assay				J Nat Prod 77: 563-70 (2014) Article DOI: 10.1021/np400817j BindingDB Entry DOI: 10.7270/Q23J3GZJ
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50021398 (CHEBI:18088 \| FORMONONETIN \| NSC-93360) Show SMILES COc1ccc(cc1)-c1coc2cc(O)ccc2c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Jishou University Curated by ChEMBL					Assay Description Inhibition of Helicobacter pylori ATCC 43504 urease-mediated ammonia production preincubated for 1.5 hrs by indophenol method				Eur J Med Chem 63: 685-95 (2013) Article DOI: 10.1016/j.ejmech.2013.03.016 BindingDB Entry DOI: 10.7270/Q2D79FB1
Jishou University Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50021398 (CHEBI:18088 \| FORMONONETIN \| NSC-93360) Show SMILES COc1ccc(cc1)-c1coc2cc(O)ccc2c1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sunchon National University Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells preincubated for 10 mins followed by addition of benzylamine...				Bioorg Med Chem Lett 26: 4714-4719 (2016) Article DOI: 10.1016/j.bmcl.2016.08.044
Sunchon National University Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50021398 (CHEBI:18088 \| FORMONONETIN \| NSC-93360) Show SMILES COc1ccc(cc1)-c1coc2cc(O)ccc2c1=O Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sunchon National University Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells preincubated for 10 mins followed by addition of kynuramine ...				Bioorg Med Chem Lett 26: 4714-4719 (2016) Article DOI: 10.1016/j.bmcl.2016.08.044
Sunchon National University Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase (Mus musculus)	BDBM50021398 (CHEBI:18088 \| FORMONONETIN \| NSC-93360) Show SMILES COc1ccc(cc1)-c1coc2cc(O)ccc2c1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sunchon National University Curated by ChEMBL					Assay Description Inhibition of mouse MAO-A preincubated for 15 mins followed by addition of kynuramine as substrate measured after 30 mins by fluorometric analysis				Bioorg Med Chem Lett 26: 4714-4719 (2016) Article DOI: 10.1016/j.bmcl.2016.08.044
Sunchon National University Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase (Mus musculus)	BDBM50021398 (CHEBI:18088 \| FORMONONETIN \| NSC-93360) Show SMILES COc1ccc(cc1)-c1coc2cc(O)ccc2c1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sunchon National University Curated by ChEMBL					Assay Description Inhibition of mouse MAO-B preincubated for 15 mins followed by addition of kynuramine as substrate measured after 30 mins by fluorometric analysis				Bioorg Med Chem Lett 26: 4714-4719 (2016) Article DOI: 10.1016/j.bmcl.2016.08.044
Sunchon National University Curated by ChEMBL					More data for this Ligand-Target Pair
Interleukin-2 (IL-2) (Homo sapiens (Human))	BDBM50021398 (CHEBI:18088 \| FORMONONETIN \| NSC-93360) Show SMILES COc1ccc(cc1)-c1coc2cc(O)ccc2c1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.47E+3	n/a	n/a	n/a	n/a	n/a
The Second People's Hospital of Fujian Provinc Curated by ChEMBL					Assay Description Binding affinity to IL-2 (unknown origin)				Eur J Med Chem 83: 294-306 (2014) Article DOI: 10.1016/j.ejmech.2014.06.037 BindingDB Entry DOI: 10.7270/Q2NG4S7H
					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus)	BDBM50021398 (CHEBI:18088 \| FORMONONETIN \| NSC-93360) Show SMILES COc1ccc(cc1)-c1coc2cc(O)ccc2c1=O Show InChI	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Inhibition of Influenza A virus J/8178/09 neuraminidase by chemiluminescence based assay				J Nat Prod 77: 563-70 (2014) Article DOI: 10.1021/np400817j BindingDB Entry DOI: 10.7270/Q23J3GZJ
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair