BDBM64871 N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide::N-(6-chloro-3-pyridinyl)-4-fluorobenzamide::N-(6-chloro-3-pyridyl)-4-fluoro-benzamide::N-(6-chloropyridin-3-yl)-4-fluorobenzamide::ZTZ240::cid_3780776
SMILES: Fc1ccc(cc1)C(=O)Nc1ccc(Cl)nc1
InChI Key: InChIKey=URPKVELJRWKNQS-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Potassium voltage-gated channel subfamily KQT member 2 (Rattus norvegicus) | BDBM64871 (N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | PDB PCBioAssay | n/a | n/a | n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Mode of Action, Electrophysiology Source (MLPCN Center Name): Johns Hopkins Ion Channel... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2KW5DHF | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Potassium voltage-gated channel subfamily KQT member 2 (Rattus norvegicus) | BDBM64871 (N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | PDB PCBioAssay | n/a | n/a | n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Mode of Action, Electrophysiology Source (MLPCN Center Name): Johns Hopkins Ion Channel... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2Z31X37 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Potassium voltage-gated channel subfamily E/KQT member 1 (Homo sapiens (Human)) | BDBM64871 (N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide ...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 6.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonist activity at KCNQ1/MINK expressed in CHO cells assessed as inhibition of KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induct... | ACS Med Chem Lett 2: 481-484 (2011) Article DOI: 10.1021/ml200053x BindingDB Entry DOI: 10.7270/Q2R49RVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human)) | BDBM64871 (N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide ...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 980 | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Agonist activity at KCNQ2/KCNQ3 expressed in CHO cells assessed as increase in KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induction ... | ACS Med Chem Lett 2: 481-484 (2011) Article DOI: 10.1021/ml200053x BindingDB Entry DOI: 10.7270/Q2R49RVJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM64871 (N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | n/a | 1.14E+5 | n/a | n/a | n/a | n/a | n/a |
Amgen, Inc. Curated by ChEMBL | Assay Description Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysis | J Med Chem 59: 3732-49 (2016) BindingDB Entry DOI: 10.7270/Q2RF5WXP | |||||||||||
More data for this Ligand-Target Pair |