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BDBM50263016 CHEMBL477560::hematoxylene

SMILES: Oc1ccc(CC2=Cc3ccc(O)c(O)c3OC2)cc1O

InChI Key: InChIKey=YXQXLHSRJUFMFD-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50263016   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50263016
PNG
(CHEMBL477560 | hematoxylene)
Show SMILES Oc1ccc(CC2=Cc3ccc(O)c(O)c3OC2)cc1O |t:6|
Show InChI InChI=1S/C16H14O5/c17-12-3-1-9(7-14(12)19)5-10-6-11-2-4-13(18)15(20)16(11)21-8-10/h1-4,6-7,17-20H,5,8H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Src (unknown origin) by ELISA


J Med Chem 51: 4419-29 (2008)


Article DOI: 10.1021/jm701501x
BindingDB Entry DOI: 10.7270/Q2N879MQ
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50263016
PNG
(CHEMBL477560 | hematoxylene)
Show SMILES Oc1ccc(CC2=Cc3ccc(O)c(O)c3OC2)cc1O |t:6|
Show InChI InChI=1S/C16H14O5/c17-12-3-1-9(7-14(12)19)5-10-6-11-2-4-13(18)15(20)16(11)21-8-10/h1-4,6-7,17-20H,5,8H2
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 760n/an/an/an/an/an/a



Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) by ELISA


J Med Chem 51: 4419-29 (2008)


Article DOI: 10.1021/jm701501x
BindingDB Entry DOI: 10.7270/Q2N879MQ
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50263016
PNG
(CHEMBL477560 | hematoxylene)
Show SMILES Oc1ccc(CC2=Cc3ccc(O)c(O)c3OC2)cc1O |t:6|
Show InChI InChI=1S/C16H14O5/c17-12-3-1-9(7-14(12)19)5-10-6-11-2-4-13(18)15(20)16(11)21-8-10/h1-4,6-7,17-20H,5,8H2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.90E+3n/an/an/an/an/an/a



Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of cKit (unknown origin) by ELISA


J Med Chem 51: 4419-29 (2008)


Article DOI: 10.1021/jm701501x
BindingDB Entry DOI: 10.7270/Q2N879MQ
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50263016
PNG
(CHEMBL477560 | hematoxylene)
Show SMILES Oc1ccc(CC2=Cc3ccc(O)c(O)c3OC2)cc1O |t:6|
Show InChI InChI=1S/C16H14O5/c17-12-3-1-9(7-14(12)19)5-10-6-11-2-4-13(18)15(20)16(11)21-8-10/h1-4,6-7,17-20H,5,8H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.60E+3n/an/an/an/an/an/a



Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of KDR (unknown origin) by ELISA


J Med Chem 51: 4419-29 (2008)


Article DOI: 10.1021/jm701501x
BindingDB Entry DOI: 10.7270/Q2N879MQ
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM50263016
PNG
(CHEMBL477560 | hematoxylene)
Show SMILES Oc1ccc(CC2=Cc3ccc(O)c(O)c3OC2)cc1O |t:6|
Show InChI InChI=1S/C16H14O5/c17-12-3-1-9(7-14(12)19)5-10-6-11-2-4-13(18)15(20)16(11)21-8-10/h1-4,6-7,17-20H,5,8H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 600n/an/an/an/an/an/a



Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 (unknown origin) by ELISA


J Med Chem 51: 4419-29 (2008)


Article DOI: 10.1021/jm701501x
BindingDB Entry DOI: 10.7270/Q2N879MQ
More data for this
Ligand-Target Pair