BDBM100347 US8501981, 166

SMILES: CC(C)(NC(=O)c1ccc2ccccc2c1C#CCCCc1ccccc1)C(O)=O

InChI Key: InChIKey=NXCJIJUWVULEDG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100347   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM100347 (US8501981, 166) Show SMILES CC(C)(NC(=O)c1ccc2ccccc2c1C#CCCCc1ccccc1)C(O)=O Show InChI InChI=1S/C26H25NO3/c1-26(2,25(29)30)27-24(28)23-18-17-20-14-9-10-15-21(20)22(23)16-8-4-7-13-19-11-5-3-6-12-19/h3,5-6,9-12,14-15,17-18H,4,7,13H2,1-2H3,(H,27,28)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
SANOFI US Patent					Assay Description CXCR2 inhibition using calcium fluorescence assay (FLIPR).				US Patent US8501981 (2013) BindingDB Entry DOI: 10.7270/Q24Q7SMB
					More data for this Ligand-Target Pair