BDBM100716 US8507676, 65

SMILES: C\C(=N/OCCCCO)c1ccc2nnc(Cc3c(F)cc4ncccc4c3F)n2n1

InChI Key: InChIKey=BFKVBBCTXJHDSX-XODNFHPESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100716   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM100716 (US8507676, 65) Show SMILES C\C(=N/OCCCCO)c1ccc2nnc(Cc3c(F)cc4ncccc4c3F)n2n1 Show InChI InChI=1S/C21H20F2N6O2/c1-13(28-31-10-3-2-9-30)17-6-7-19-25-26-20(29(19)27-17)11-15-16(22)12-18-14(21(15)23)5-4-8-24-18/h4-8,12,30H,2-3,9-11H2,1H3/b28-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8507676 (2013) BindingDB Entry DOI: 10.7270/Q2MS3RC9
					More data for this Ligand-Target Pair