BDBM100759 US8507683, 10

SMILES: CNC(=O)c1c(oc2ccc(c(F)c12)-c1cc(ccc1C)C(=O)NC1(COC1)c1ncccn1)-c1ccc(F)cc1

InChI Key: InChIKey=RLOLEIFPKFPFMB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100759   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM100759 (US8507683, 10) Show SMILES CNC(=O)c1c(oc2ccc(c(F)c12)-c1cc(ccc1C)C(=O)NC1(COC1)c1ncccn1)-c1ccc(F)cc1 Show InChI InChI=1S/C31H24F2N4O4/c1-17-4-5-19(28(38)37-31(15-40-16-31)30-35-12-3-13-36-30)14-22(17)21-10-11-23-24(26(21)33)25(29(39)34-2)27(41-23)18-6-8-20(32)9-7-18/h3-14H,15-16H2,1-2H3,(H,34,39)(H,37,38)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HCV NS5B enzyme assay.				US Patent US8507683 (2013) BindingDB Entry DOI: 10.7270/Q2C827XJ
					More data for this Ligand-Target Pair