BDBM100797 US8507533, 105

SMILES: CC(C)CC(Nc1cnc(c(C)c1)-n1cc(cn1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O

InChI Key: InChIKey=HWVPKJAIAFMSII-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100797   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pro-glucagon (Homo sapiens (Human))	BDBM100797 (US8507533, 105) Show SMILES CC(C)CC(Nc1cnc(c(C)c1)-n1cc(cn1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C25H28F3N5O3/c1-15(2)10-21(17-4-6-18(7-5-17)24(36)29-9-8-22(34)35)32-20-11-16(3)23(30-13-20)33-14-19(12-31-33)25(26,27)28/h4-7,11-15,21,32H,8-10H2,1-3H3,(H,29,36)(H,34,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	69.8	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Pfizer Inc. US Patent					Assay Description The Glucagon SPA assay is used to determine the ability of test compounds to block the binding of glucagon-cex to the glucagon receptors.				US Patent US8507533 (2013) BindingDB Entry DOI: 10.7270/Q23R0RGH
					More data for this Ligand-Target Pair