BDBM101347 US9695151, 13

SMILES: CC(C)S(=O)(=O)N1CC(C1)N(C)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C

InChI Key: InChIKey=XPTWRGUPFYGCCR-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 101347   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM101347 (US9695151, 13) Show SMILES CC(C)S(=O)(=O)N1CC(C1)N(C)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C22H27ClN4O3S/c1-14(2)31(29,30)26-12-18(13-26)25(5)16-9-17(11-24-10-16)27-21(28)19-7-6-15(23)8-20(19)22(27,3)4/h6-11,14,18H,12-13H2,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	37	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co...				US Patent US9695151 (2017) BindingDB Entry DOI: 10.7270/Q2KD1W22
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM101347 (US9695151, 13) Show SMILES CC(C)S(=O)(=O)N1CC(C1)N(C)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C22H27ClN4O3S/c1-14(2)31(29,30)26-12-18(13-26)25(5)16-9-17(11-24-10-16)27-21(28)19-7-6-15(23)8-20(19)22(27,3)4/h6-11,14,18H,12-13H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co...				US Patent US9695151 (2017) BindingDB Entry DOI: 10.7270/Q2KD1W22
					More data for this Ligand-Target Pair