BDBM101486 US8524710, 63::US8530652, 13::US8530652, 57

SMILES: CC1(C)N(Cc2c(Nc3nc(Cl)nc(n3)N3CCC[C@H]3C(N)=O)[nH]nc12)C(=O)NC1C[C@@H]1c1ccccc1

InChI Key: InChIKey=WIOQQOCSMKRLGA-AQYZNVCMSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 101486   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human))	BDBM101486 (US8524710, 63 | US8530652, 13 | US8530652, 57) Show SMILES CC1(C)N(Cc2c(Nc3nc(Cl)nc(n3)N3CCC[C@H]3C(N)=O)[nH]nc12)C(=O)NC1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C25H29ClN10O2/c1-25(2)18-15(12-36(25)24(38)28-16-11-14(16)13-7-4-3-5-8-13)20(34-33-18)29-22-30-21(26)31-23(32-22)35-10-6-9-17(35)19(27)37/h3-5,7-8,14,16-17H,6,9-12H2,1-2H3,(H2,27,37)(H,28,38)(H2,29,30,31,32,33,34)/t14-,16?,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent					Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...				US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4
					More data for this Ligand-Target Pair