BDBM101490 US8524710, 68::US8530652, 17::US8530652, 61

SMILES: CNC(=O)[C@@H]1CCCN1c1nc(Nc2[nH]nc3c2CN(C(=O)NC2CC2c2ccccc2)C3(C)C)nc(OC)n1

InChI Key: InChIKey=VXZYDTWAWCETNV-KVZIAJEVSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 101490   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human))	BDBM101490 (US8524710, 68 | US8530652, 17 | US8530652, 61) Show SMILES CNC(=O)[C@@H]1CCCN1c1nc(Nc2[nH]nc3c2CN(C(=O)NC2CC2c2ccccc2)C3(C)C)nc(OC)n1 |r| Show InChI InChI=1S/C27H34N10O3/c1-27(2)20-17(14-37(27)26(39)29-18-13-16(18)15-9-6-5-7-10-15)21(35-34-20)30-23-31-24(33-25(32-23)40-4)36-12-8-11-19(36)22(38)28-3/h5-7,9-10,16,18-19H,8,11-14H2,1-4H3,(H,28,38)(H,29,39)(H2,30,31,32,33,34,35)/t16?,18?,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent					Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...				US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4
					More data for this Ligand-Target Pair