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BDBM101551 US8530494, 213::US8530652, 130::US8530652, 78

SMILES: CN(C)C[C@@H](OC(=O)N1Cc2c(Nc3ncnc4n(C)cnc34)[nH]nc2C1(C)C)c1ccccc1

InChI Key: InChIKey=IPZRNWVYAFZMLF-QGZVFWFLSA-N

Data: 1 KI  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 101551   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase PAK 4


(Homo sapiens (Human))		BDBM101551
PNG
(US8530494, 213 | US8530652, 130 | US8530652, 78)
Show SMILES CN(C)C[C@@H](OC(=O)N1Cc2c(Nc3ncnc4n(C)cnc34)[nH]nc2C1(C)C)c1ccccc1 |r|
Show InChI InChI=1S/C24H29N9O2/c1-24(2)19-16(20(30-29-19)28-21-18-22(26-13-25-21)32(5)14-27-18)11-33(24)23(34)35-17(12-31(3)4)15-9-7-6-8-10-15/h6-10,13-14,17H,11-12H2,1-5H3,(H2,25,26,28,29,30)/t17-/m1/s1
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Similars
US Patent
 330n/an/an/a>4.00E+3n/an/an/an/a



Agouron Pharmaceuticals, Inc.; Pfizer Inc.

US Patent


Assay Description
The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...

US Patent US8530652 (2013)


BindingDB Entry DOI: 10.7270/Q2F18XC4
More data for this
Ligand-Target Pair