BDBM101676 US9695160, 20::US9796707, Compound 20

SMILES: Cc1ccc(o1)C(=O)Nc1cc(ccc1N1CCN(Cc2ccccc2)CC1)C(F)(F)F

InChI Key: InChIKey=SEPKIGSWMOPZPB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 101676   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase SRPK1 (Homo sapiens (Human))	BDBM101676 (US9695160, 20 | US9796707, Compound 20) Show SMILES Cc1ccc(o1)C(=O)Nc1cc(ccc1N1CCN(Cc2ccccc2)CC1)C(F)(F)F Show InChI InChI=1S/C24H24F3N3O2/c1-17-7-10-22(32-17)23(31)28-20-15-19(24(25,26)27)8-9-21(20)30-13-11-29(12-14-30)16-18-5-3-2-4-6-18/h2-10,15H,11-14,16H2,1H3,(H,28,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
The University of Nottingham; NewSouth Innovations PTY Limited US Patent					Assay Description Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....				US Patent US9796707 (2017) BindingDB Entry DOI: 10.7270/Q2125VTM
					More data for this Ligand-Target Pair
SRSF protein kinase 1 (SRPK1) (Homo sapiens (Human))	BDBM101676 (US9695160, 20 | US9796707, Compound 20) Show SMILES Cc1ccc(o1)C(=O)Nc1cc(ccc1N1CCN(Cc2ccccc2)CC1)C(F)(F)F Show InChI InChI=1S/C24H24F3N3O2/c1-17-7-10-22(32-17)23(31)28-20-15-19(24(25,26)27)8-9-21(20)30-13-11-29(12-14-30)16-18-5-3-2-4-6-18/h2-10,15H,11-14,16H2,1H3,(H,28,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	30
The University of Nottingham; NewSouth Innovations PTY Limited US Patent					Assay Description Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....				US Patent US9695160 (2017) BindingDB Entry DOI: 10.7270/Q2639MW1
					More data for this Ligand-Target Pair