BDBM101734 US9695160, 31::US9796707, Compound 31

SMILES: CSc1nccc(CN2CCN(CC2)c2ccc(cc2NC(=O)c2ccc(C)o2)C(F)(F)F)n1

InChI Key: InChIKey=RXWYVJKKPWSHBQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 101734   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase SRPK1 (Homo sapiens (Human))	BDBM101734 (US9695160, 31 | US9796707, Compound 31) Show SMILES CSc1nccc(CN2CCN(CC2)c2ccc(cc2NC(=O)c2ccc(C)o2)C(F)(F)F)n1 Show InChI InChI=1S/C23H24F3N5O2S/c1-15-3-6-20(33-15)21(32)29-18-13-16(23(24,25)26)4-5-19(18)31-11-9-30(10-12-31)14-17-7-8-27-22(28-17)34-2/h3-8,13H,9-12,14H2,1-2H3,(H,29,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
The University of Nottingham; NewSouth Innovations PTY Limited US Patent					Assay Description Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....				US Patent US9796707 (2017) BindingDB Entry DOI: 10.7270/Q2125VTM
					More data for this Ligand-Target Pair
SRSF protein kinase 1 (SRPK1) (Homo sapiens (Human))	BDBM101734 (US9695160, 31 | US9796707, Compound 31) Show SMILES CSc1nccc(CN2CCN(CC2)c2ccc(cc2NC(=O)c2ccc(C)o2)C(F)(F)F)n1 Show InChI InChI=1S/C23H24F3N5O2S/c1-15-3-6-20(33-15)21(32)29-18-13-16(23(24,25)26)4-5-19(18)31-11-9-30(10-12-31)14-17-7-8-27-22(28-17)34-2/h3-8,13H,9-12,14H2,1-2H3,(H,29,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	30
The University of Nottingham; NewSouth Innovations PTY Limited US Patent					Assay Description Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....				US Patent US9695160 (2017) BindingDB Entry DOI: 10.7270/Q2639MW1
					More data for this Ligand-Target Pair