BindingDB logo
myBDB logout

null

SMILES: Oc1cc(\C=C\C(=S)NCc2cc(O)c(O)c(O)c2Br)cc(Br)c1O

InChI Key: InChIKey=CIYVRSWUTFVUBD-OWOJBTEDSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 101912   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))		BDBM101912
PNG
(US8536227, 4)
Show SMILES Oc1cc(\C=C\C(=S)NCc2cc(O)c(O)c(O)c2Br)cc(Br)c1O
Show InChI InChI=1S/C16H13Br2NO5S/c17-9-3-7(4-10(20)14(9)22)1-2-12(25)19-6-8-5-11(21)15(23)16(24)13(8)18/h1-5,20-24H,6H2,(H,19,25)/b2-1+
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 30n/an/an/an/an/an/a



Novotyr Therapeutics Ltd.

US Patent


Assay Description
Inhibition assay using IGF1R activity in a cell free kinase assay.

US Patent US8536227 (2013)


BindingDB Entry DOI: 10.7270/Q21V5CKM
More data for this
Ligand-Target Pair