BDBM101914 US8536227, 6
SMILES: Oc1cc(Br)c(\C=C\C(=S)NCc2cc(O)c(O)c(O)c2)cc1O
InChI Key: InChIKey=BOONYZWYEWWWCV-OWOJBTEDSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Insulin-like growth factor I receptor (Homo sapiens (Human)) | BDBM101914 (US8536227, 6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Novotyr Therapeutics Ltd. US Patent | Assay Description Inhibition assay using IGF1R activity in a cell free kinase assay. | US Patent US8536227 (2013) BindingDB Entry DOI: 10.7270/Q21V5CKM | |||||||||||
More data for this Ligand-Target Pair |