BDBM102460 US8536165, 41

SMILES: CCOc1cccc(c1)-c1ccc(Nc2ccc(C)cc2C(O)=O)cn1

InChI Key: InChIKey=IRWOSSUDEZEAJN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 102460   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM102460 (US8536165, 41) Show SMILES CCOc1cccc(c1)-c1ccc(Nc2ccc(C)cc2C(O)=O)cn1 Show InChI InChI=1S/C21H20N2O3/c1-3-26-17-6-4-5-15(12-17)19-10-8-16(13-22-19)23-20-9-7-14(2)11-18(20)21(24)25/h4-13,23H,3H2,1-2H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	190	n/a	n/a	n/a	n/a	8.0	n/a
Almirall, S.A. US Patent					Assay Description Inhibition of human DHODH activity assay: DHODH activity and its inhibition were studied using a chromogen reduction assay with DCIP (2,6-dichloroph...				US Patent US8536165 (2013) BindingDB Entry DOI: 10.7270/Q2C24V2G
					More data for this Ligand-Target Pair