BDBM103133 US8541407, 110

SMILES: O=C(NCCc1ccc(cc1)-c1nnc2-c3ccccc3Nc3ncccc3-n12)Nc1ccccc1

InChI Key: InChIKey=OZHGPIQFTHWGIP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 103133   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM103133 (US8541407, 110) Show SMILES O=C(NCCc1ccc(cc1)-c1nnc2-c3ccccc3Nc3ncccc3-n12)Nc1ccccc1 Show InChI InChI=1S/C28H23N7O/c36-28(31-21-7-2-1-3-8-21)30-18-16-19-12-14-20(15-13-19)26-33-34-27-22-9-4-5-10-23(22)32-25-24(35(26)27)11-6-17-29-25/h1-15,17H,16,18H2,(H,29,32)(H2,30,31,36)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
ArQule, Inc. US Patent					Assay Description Biochemical assay using Akt AlphaScreen (Amplified Luminescent Proximity Homogeneous Assay) technology.				US Patent US8541407 (2013) BindingDB Entry DOI: 10.7270/Q2JM288F
					More data for this Ligand-Target Pair