BDBM103512 US8546370, 83

SMILES: CCN1CCN(CC1)c1cc2cc[nH]c(=O)c2c(Nc2ccc(cc2)N2CCOCC2)n1

InChI Key: InChIKey=UEWIEMDRYRSCHR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 103512   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ZAP-70 (Homo sapiens (Human))	BDBM103512 (US8546370, 83) Show SMILES CCN1CCN(CC1)c1cc2cc[nH]c(=O)c2c(Nc2ccc(cc2)N2CCOCC2)n1 Show InChI InChI=1S/C24H30N6O2/c1-2-28-9-11-30(12-10-28)21-17-18-7-8-25-24(31)22(18)23(27-21)26-19-3-5-20(6-4-19)29-13-15-32-16-14-29/h3-8,17H,2,9-16H2,1H3,(H,25,31)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
IRM LLC US Patent					Assay Description Homogenous time-resolved fluorescence assay using Syk enzyme.				US Patent US8546370 (2013) BindingDB Entry DOI: 10.7270/Q2GQ6WDM
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ZAP-70 (Homo sapiens (Human))	BDBM103512 (US8546370, 83) Show SMILES CCN1CCN(CC1)c1cc2cc[nH]c(=O)c2c(Nc2ccc(cc2)N2CCOCC2)n1 Show InChI InChI=1S/C24H30N6O2/c1-2-28-9-11-30(12-10-28)21-17-18-7-8-25-24(31)22(18)23(27-21)26-19-3-5-20(6-4-19)29-13-15-32-16-14-29/h3-8,17H,2,9-16H2,1H3,(H,25,31)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
IRM LLC US Patent					Assay Description Homogenous time-resolved fluorescence assay using Syk enzyme.				US Patent US8546370 (2013) BindingDB Entry DOI: 10.7270/Q2GQ6WDM
					More data for this Ligand-Target Pair