BindingDB logo
myBDB logout

null

SMILES: C[C@@H]1CN(CCO1)c1ccc(Nc2nc(cc3cc[nH]c(=O)c23)-c2cnc(C)nc2)cc1C

InChI Key: InChIKey=QPVOMMBRCYTAFN-MRXNPFEDSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 103526   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase ZAP-70


(Homo sapiens (Human))		BDBM103526
PNG
(US8546370, 580)
Show SMILES C[C@@H]1CN(CCO1)c1ccc(Nc2nc(cc3cc[nH]c(=O)c23)-c2cnc(C)nc2)cc1C |r|
Show InChI InChI=1S/C25H26N6O2/c1-15-10-20(4-5-22(15)31-8-9-33-16(2)14-31)29-24-23-18(6-7-26-25(23)32)11-21(30-24)19-12-27-17(3)28-13-19/h4-7,10-13,16H,8-9,14H2,1-3H3,(H,26,32)(H,29,30)/t16-/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 220n/an/an/an/an/an/a



IRM LLC

US Patent


Assay Description
Homogenous time-resolved fluorescence assay using Syk enzyme.

US Patent US8546370 (2013)


BindingDB Entry DOI: 10.7270/Q2GQ6WDM
More data for this
Ligand-Target Pair