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SMILES: Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2cncn12)-c1ccc(C#N)c(F)c1

InChI Key: InChIKey=NIFRRUQWIPLWJY-GOSISDBHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 103890   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A [151-852] (Homo sapiens (Human))	BDBM103890 (US10047086, 4 | US10640503, Example 4 | US9695168,...) Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2cncn12)-c1ccc(C#N)c(F)c1 |r| Show InChI InChI=1S/C26H23FN4O/c1-17-2-4-19(5-3-17)26-22(20-6-7-21(12-28)23(27)10-20)11-25(24-14-30-16-31(24)26)32-15-18-8-9-29-13-18/h2-7,10-11,14,16,18,29H,8-9,13,15H2,1H3/t18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	25
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay¿10 uL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 mM Na...				US Patent US9695168 (2017) BindingDB Entry DOI: 10.7270/Q2SX6BCD
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM103890 (US10047086, 4 | US10640503, Example 4 | US9695168,...) Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2cncn12)-c1ccc(C#N)c(F)c1 |r| Show InChI InChI=1S/C26H23FN4O/c1-17-2-4-19(5-3-17)26-22(20-6-7-21(12-28)23(27)10-20)11-25(24-14-30-16-31(24)26)32-15-18-8-9-29-13-18/h2-7,10-11,14,16,18,29H,8-9,13,15H2,1H3/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020)
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM103890 (US10047086, 4 | US10640503, Example 4 | US9695168,...) Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2cncn12)-c1ccc(C#N)c(F)c1 |r| Show InChI InChI=1S/C26H23FN4O/c1-17-2-4-19(5-3-17)26-22(20-6-7-21(12-28)23(27)10-20)11-25(24-14-30-16-31(24)26)32-15-18-8-9-29-13-18/h2-7,10-11,14,16,18,29H,8-9,13,15H2,1H3/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10047086 (2018) BindingDB Entry DOI: 10.7270/Q28917W4
					More data for this Ligand-Target Pair