BDBM103898 US10047086, 12::US10640503, Example 12::US9695168, 12

SMILES: CN1C(=O)Cc2cc(ccc12)-c1c(cc(OC[C@@H]2CCNC2)c2cncn12)-c1ccc(cc1)C#N

InChI Key: InChIKey=SPSDCRJQODHUFU-LJQANCHMSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 103898   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM103898 (US10047086, 12 | US10640503, Example 12 | US969516...) Show SMILES CN1C(=O)Cc2cc(ccc12)-c1c(cc(OC[C@@H]2CCNC2)c2cncn12)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C28H25N5O2/c1-32-24-7-6-21(10-22(24)11-27(32)34)28-23(20-4-2-18(13-29)3-5-20)12-26(25-15-31-17-33(25)28)35-16-19-8-9-30-14-19/h2-7,10,12,15,17,19,30H,8-9,11,14,16H2,1H3/t19-/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	25
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay¿10 uL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 mM Na...				US Patent US9695168 (2017) BindingDB Entry DOI: 10.7270/Q2SX6BCD
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM103898 (US10047086, 12 | US10640503, Example 12 | US969516...) Show SMILES CN1C(=O)Cc2cc(ccc12)-c1c(cc(OC[C@@H]2CCNC2)c2cncn12)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C28H25N5O2/c1-32-24-7-6-21(10-22(24)11-27(32)34)28-23(20-4-2-18(13-29)3-5-20)12-26(25-15-31-17-33(25)28)35-16-19-8-9-30-14-19/h2-7,10,12,15,17,19,30H,8-9,11,14,16H2,1H3/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020)
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM103898 (US10047086, 12 | US10640503, Example 12 | US969516...) Show SMILES CN1C(=O)Cc2cc(ccc12)-c1c(cc(OC[C@@H]2CCNC2)c2cncn12)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C28H25N5O2/c1-32-24-7-6-21(10-22(24)11-27(32)34)28-23(20-4-2-18(13-29)3-5-20)12-26(25-15-31-17-33(25)28)35-16-19-8-9-30-14-19/h2-7,10,12,15,17,19,30H,8-9,11,14,16H2,1H3/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10047086 (2018) BindingDB Entry DOI: 10.7270/Q28917W4
					More data for this Ligand-Target Pair