BDBM104147 US8575145, 24

SMILES: CC(C)(CO)COc1cccc2ccc(nc12)-c1nnc2ccccn12

InChI Key: InChIKey=QDMRXIVSBQLTQK-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 104147   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM104147 (US8575145, 24) Show SMILES CC(C)(CO)COc1cccc2ccc(nc12)-c1nnc2ccccn12 Show InChI InChI=1S/C20H20N4O2/c1-20(2,12-25)13-26-16-7-5-6-14-9-10-15(21-18(14)16)19-23-22-17-8-3-4-11-24(17)19/h3-11,25H,12-13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.4	22
Array BioPharma Inc. US Patent					Assay Description The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...				US Patent US8575145 (2013) BindingDB Entry DOI: 10.7270/Q2M90797
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PIM-3 (Rattus norvegicus (Rat))	BDBM104147 (US8575145, 24) Show SMILES CC(C)(CO)COc1cccc2ccc(nc12)-c1nnc2ccccn12 Show InChI InChI=1S/C20H20N4O2/c1-20(2,12-25)13-26-16-7-5-6-14-9-10-15(21-18(14)16)19-23-22-17-8-3-4-11-24(17)19/h3-11,25H,12-13H2,1-2H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.4	22
Array BioPharma Inc. US Patent					Assay Description The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...				US Patent US8575145 (2013) BindingDB Entry DOI: 10.7270/Q2M90797
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM104147 (US8575145, 24) Show SMILES CC(C)(CO)COc1cccc2ccc(nc12)-c1nnc2ccccn12 Show InChI InChI=1S/C20H20N4O2/c1-20(2,12-25)13-26-16-7-5-6-14-9-10-15(21-18(14)16)19-23-22-17-8-3-4-11-24(17)19/h3-11,25H,12-13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	77	n/a	n/a	n/a	n/a	7.4	22
Array BioPharma Inc. US Patent					Assay Description The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...				US Patent US8575145 (2013) BindingDB Entry DOI: 10.7270/Q2M90797
					More data for this Ligand-Target Pair