BDBM104378 US8575186, 141

SMILES: Cc1cc(cc2c3C4CCC(Cc3n(C)c12)N4)S(=O)(=O)c1csc2ccccc12

InChI Key: InChIKey=DGOIEPCGZNYRHM-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 104378   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM104378 (US8575186, 141) Show SMILES Cc1cc(cc2c3C4CCC(Cc3n(C)c12)N4)S(=O)(=O)c1csc2ccccc12 |THB:5:6:16:8.9,13:12:16:8.9| Show InChI InChI=1S/C23H22N2O2S2/c1-13-9-15(29(26,27)21-12-28-20-6-4-3-5-16(20)21)11-17-22-18-8-7-14(24-18)10-19(22)25(2)23(13)17/h3-6,9,11-12,14,18,24H,7-8,10H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research, Inc. US Patent					Assay Description The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...				US Patent US8575186 (2013) BindingDB Entry DOI: 10.7270/Q2BR8QTS
					More data for this Ligand-Target Pair