BDBM104454 US8575186, 217/218::US8575186, 234

SMILES: COc1cc(cc2c3C4CCC(Cc3n(C)c12)N4)S(=O)(=O)c1ccccc1F

InChI Key: InChIKey=LXEZJBNRKHCPSS-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 104454   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM104454 (US8575186, 217/218 | US8575186, 234) Show SMILES COc1cc(cc2c3C4CCC(Cc3n(C)c12)N4)S(=O)(=O)c1ccccc1F |THB:6:7:17:9.10,14:13:17:9.10| Show InChI InChI=1S/C21H21FN2O3S/c1-24-17-9-12-7-8-16(23-12)20(17)14-10-13(11-18(27-2)21(14)24)28(25,26)19-6-4-3-5-15(19)22/h3-6,10-12,16,23H,7-9H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research, Inc. US Patent					Assay Description The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...				US Patent US8575186 (2013) BindingDB Entry DOI: 10.7270/Q2BR8QTS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM104454 (US8575186, 217/218 | US8575186, 234) Show SMILES COc1cc(cc2c3C4CCC(Cc3n(C)c12)N4)S(=O)(=O)c1ccccc1F |THB:6:7:17:9.10,14:13:17:9.10| Show InChI InChI=1S/C21H21FN2O3S/c1-24-17-9-12-7-8-16(23-12)20(17)14-10-13(11-18(27-2)21(14)24)28(25,26)19-6-4-3-5-15(19)22/h3-6,10-12,16,23H,7-9H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research, Inc. US Patent					Assay Description The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...				US Patent US8575186 (2013) BindingDB Entry DOI: 10.7270/Q2BR8QTS
					More data for this Ligand-Target Pair