BDBM104529 US8575201, 20

SMILES: Cn1cc(-c2nc(no2)C2(CCC2)c2ccc(nc2)-c2cnc(N)nc2)c(n1)C(F)(F)F

InChI Key: InChIKey=XMIJKOKEOFELFR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 104529   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM104529 (US8575201, 20) Show SMILES Cn1cc(-c2nc(no2)C2(CCC2)c2ccc(nc2)-c2cnc(N)nc2)c(n1)C(F)(F)F Show InChI InChI=1S/C20H17F3N8O/c1-31-10-13(15(29-31)20(21,22)23)16-28-17(30-32-16)19(5-2-6-19)12-3-4-14(25-9-12)11-7-26-18(24)27-8-11/h3-4,7-10H,2,5-6H2,1H3,(H2,24,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Compounds area assessed for the ability to bind to FLAP in a binding assay that measures compound-specific displacement of an iodinated (125I) FLAP i...				US Patent US8575201 (2013) BindingDB Entry DOI: 10.7270/Q2ZK5FBX
					More data for this Ligand-Target Pair