BDBM104636 US8575201, 127

SMILES: Cn1ccc(n1)-c1nc(no1)C1(CCC1)c1ccc(nc1)-c1cnc(N)nc1

InChI Key: InChIKey=APGCHGODXNGUTQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 104636   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM104636 (US8575201, 127) Show SMILES Cn1ccc(n1)-c1nc(no1)C1(CCC1)c1ccc(nc1)-c1cnc(N)nc1 Show InChI InChI=1S/C19H18N8O/c1-27-8-5-15(25-27)16-24-17(26-28-16)19(6-2-7-19)13-3-4-14(21-11-13)12-9-22-18(20)23-10-12/h3-5,8-11H,2,6-7H2,1H3,(H2,20,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Compounds area assessed for the ability to bind to FLAP in a binding assay that measures compound-specific displacement of an iodinated (125I) FLAP i...				US Patent US8575201 (2013) BindingDB Entry DOI: 10.7270/Q2ZK5FBX
					More data for this Ligand-Target Pair