BDBM104677 US8575201, 168

SMILES: CNc1cnc(cn1)-c1ccc(cn1)C1(CCC1)c1noc(n1)-c1cnn(C)c1

InChI Key: InChIKey=QDELDABBWWAQRY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 104677   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM104677 (US8575201, 168) Show SMILES CNc1cnc(cn1)-c1ccc(cn1)C1(CCC1)c1noc(n1)-c1cnn(C)c1 Show InChI InChI=1S/C20H20N8O/c1-21-17-11-23-16(10-24-17)15-5-4-14(9-22-15)20(6-3-7-20)19-26-18(29-27-19)13-8-25-28(2)12-13/h4-5,8-12H,3,6-7H2,1-2H3,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Compounds area assessed for the ability to bind to FLAP in a binding assay that measures compound-specific displacement of an iodinated (125I) FLAP i...				US Patent US8575201 (2013) BindingDB Entry DOI: 10.7270/Q2ZK5FBX
					More data for this Ligand-Target Pair