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SMILES: Cn1cc(cn1)-c1nc(no1)C1(CCC1)c1ccc(nc1)-c1cnc(N)cn1

InChI Key: InChIKey=VHGUGHVMQLBNIJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 104683   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Arachidonate 5-lipoxygenase-activating protein


(Homo sapiens (Human))		BDBM104683
PNG
(US8575201, 174)
Show SMILES Cn1cc(cn1)-c1nc(no1)C1(CCC1)c1ccc(nc1)-c1cnc(N)cn1
Show InChI InChI=1S/C19H18N8O/c1-27-11-12(7-24-27)17-25-18(26-28-17)19(5-2-6-19)13-3-4-14(21-8-13)15-9-23-16(20)10-22-15/h3-4,7-11H,2,5-6H2,1H3,(H2,20,23)
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Similars
US Patent
n/an/a 39n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Compounds area assessed for the ability to bind to FLAP in a binding assay that measures compound-specific displacement of an iodinated (125I) FLAP i...

US Patent US8575201 (2013)


BindingDB Entry DOI: 10.7270/Q2ZK5FBX
More data for this
Ligand-Target Pair