BDBM105000 US8575364, 9

SMILES: COc1ccc(cc1OC1CNC1)-c1ccccc1OC

InChI Key: InChIKey=LOWWCEBZQVXEGV-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 105000   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM105000 (US8575364, 9) Show SMILES COc1ccc(cc1OC1CNC1)-c1ccccc1OC Show InChI InChI=1S/C17H19NO3/c1-19-15-6-4-3-5-14(15)12-7-8-16(20-2)17(9-12)21-13-10-18-11-13/h3-9,13,18H,10-11H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...				US Patent US8957059 (2015) BindingDB Entry DOI: 10.7270/Q22Z1472
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM105000 (US8575364, 9) Show SMILES COc1ccc(cc1OC1CNC1)-c1ccccc1OC Show InChI InChI=1S/C17H19NO3/c1-19-15-6-4-3-5-14(15)12-7-8-16(20-2)17(9-12)21-13-10-18-11-13/h3-9,13,18H,10-11H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Compound affinity for the rat 5-HT7 receptor subtype was evaluated by competitive radioligand binding assay using 5-carboxamido[H3]typtamine ([3H]5-C...				US Patent US8575364 (2013) BindingDB Entry DOI: 10.7270/Q2J9651G
					More data for this Ligand-Target Pair