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SMILES: COc1ccc(cc1OC1CNC1)-c1cccc(C)c1

InChI Key: InChIKey=HFHMCIJUDXIIBV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 105004   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM105004 (US8575364, 13) Show SMILES COc1ccc(cc1OC1CNC1)-c1cccc(C)c1 Show InChI InChI=1S/C17H19NO2/c1-12-4-3-5-13(8-12)14-6-7-16(19-2)17(9-14)20-15-10-18-11-15/h3-9,15,18H,10-11H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...				US Patent US8957059 (2015) BindingDB Entry DOI: 10.7270/Q22Z1472
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM105004 (US8575364, 13) Show SMILES COc1ccc(cc1OC1CNC1)-c1cccc(C)c1 Show InChI InChI=1S/C17H19NO2/c1-12-4-3-5-13(8-12)14-6-7-16(19-2)17(9-14)20-15-10-18-11-15/h3-9,15,18H,10-11H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Compound affinity for the rat 5-HT7 receptor subtype was evaluated by competitive radioligand binding assay using 5-carboxamido[H3]typtamine ([3H]5-C...				US Patent US8575364 (2013) BindingDB Entry DOI: 10.7270/Q2J9651G
					More data for this Ligand-Target Pair