BDBM105046 US8575364, 55

SMILES: CN1CCC(C1)c1ccccc1-c1ccc(C)cc1

InChI Key: InChIKey=PEDPMDVDRXJXTE-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 105046   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM105046 (US8575364, 55) Show SMILES CN1CCC(C1)c1ccccc1-c1ccc(C)cc1 Show InChI InChI=1S/C18H21N/c1-14-7-9-15(10-8-14)17-5-3-4-6-18(17)16-11-12-19(2)13-16/h3-10,16H,11-13H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...				US Patent US8957059 (2015) BindingDB Entry DOI: 10.7270/Q22Z1472
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM105046 (US8575364, 55) Show SMILES CN1CCC(C1)c1ccccc1-c1ccc(C)cc1 Show InChI InChI=1S/C18H21N/c1-14-7-9-15(10-8-14)17-5-3-4-6-18(17)16-11-12-19(2)13-16/h3-10,16H,11-13H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Compound affinity for the rat 5-HT7 receptor subtype was evaluated by competitive radioligand binding assay using 5-carboxamido[H3]typtamine ([3H]5-C...				US Patent US8575364 (2013) BindingDB Entry DOI: 10.7270/Q2J9651G
					More data for this Ligand-Target Pair