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SMILES: Cc1cc(cc(C)n1)-c1n[nH]c2ccnc(OC3CCOCC3)c12

InChI Key: InChIKey=DXZPXAGWNZTVPO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 105093   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Leucine-rich repeat serine/threonine-protein kinase 2


(Homo sapiens (Human))		BDBM105093
PNG
(US8569281, 100)
Show SMILES Cc1cc(cc(C)n1)-c1n[nH]c2ccnc(OC3CCOCC3)c12
Show InChI InChI=1S/C18H20N4O2/c1-11-9-13(10-12(2)20-11)17-16-15(21-22-17)3-6-19-18(16)24-14-4-7-23-8-5-14/h3,6,9-10,14H,4-5,7-8H2,1-2H3,(H,21,22)
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Similars
US Patent
 5n/an/an/an/an/an/an/an/a



Medical Research Council Technology; Genentech, Inc.

US Patent


Assay Description
This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining Kiapp, IC50 or percent inhibition values.

US Patent US8569281 (2013)


BindingDB Entry DOI: 10.7270/Q2DN43PM
More data for this
Ligand-Target Pair