BDBM105101 US8569281, 111

SMILES: CC1CCCN(C1)c1cc(ccn1)-c1n[nH]c2ccnc(OC3CCOCC3)c12

InChI Key: InChIKey=OQXUATNGMFCOAY-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 105101   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM105101 (US8569281, 111) Show SMILES CC1CCCN(C1)c1cc(ccn1)-c1n[nH]c2ccnc(OC3CCOCC3)c12 Show InChI InChI=1S/C22H27N5O2/c1-15-3-2-10-27(14-15)19-13-16(4-8-23-19)21-20-18(25-26-21)5-9-24-22(20)29-17-6-11-28-12-7-17/h4-5,8-9,13,15,17H,2-3,6-7,10-12,14H2,1H3,(H,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology; Genentech, Inc. US Patent					Assay Description This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining Kiapp, IC50 or percent inhibition values.				US Patent US8569281 (2013) BindingDB Entry DOI: 10.7270/Q2DN43PM
					More data for this Ligand-Target Pair