BDBM105148 US8569281, 175

SMILES: Cn1cccc(Nc2n[nH]c3ccnc(OC4CCOCC4)c23)c1=O

InChI Key: InChIKey=NDCINVDYIZBLBH-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 105148   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM105148 (US8569281, 175) Show SMILES Cn1cccc(Nc2n[nH]c3ccnc(OC4CCOCC4)c23)c1=O Show InChI InChI=1S/C17H19N5O3/c1-22-8-2-3-13(17(22)23)19-15-14-12(20-21-15)4-7-18-16(14)25-11-5-9-24-10-6-11/h2-4,7-8,11H,5-6,9-10H2,1H3,(H2,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology; Genentech, Inc. US Patent					Assay Description This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining Kiapp, IC50 or percent inhibition values.				US Patent US8569281 (2013) BindingDB Entry DOI: 10.7270/Q2DN43PM
					More data for this Ligand-Target Pair