BDBM105576 US10047086, 102::US10640503, Example 102::US9695168, 102

SMILES: CN1CCC[C@@H](COc2nc(-c3ccc(C#N)c(F)c3)c(-c3ccc4N(C)C(=O)CCc4c3)n3cncc23)C1

InChI Key: InChIKey=PPZGJHAGGVVGIJ-LJQANCHMSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 105576   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105576 (US10047086, 102 | US10640503, Example 102 | US9695...) Show SMILES CN1CCC[C@@H](COc2nc(-c3ccc(C#N)c(F)c3)c(-c3ccc4N(C)C(=O)CCc4c3)n3cncc23)C1 |r| Show InChI InChI=1S/C30H29FN6O2/c1-35-11-3-4-19(16-35)17-39-30-26-15-33-18-37(26)29(28(34-30)21-5-6-23(14-32)24(31)13-21)22-7-9-25-20(12-22)8-10-27(38)36(25)2/h5-7,9,12-13,15,18-19H,3-4,8,10-11,16-17H2,1-2H3/t19-/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	25
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay¿10 uL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 mM Na...				US Patent US9695168 (2017) BindingDB Entry DOI: 10.7270/Q2SX6BCD
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105576 (US10047086, 102 | US10640503, Example 102 | US9695...) Show SMILES CN1CCC[C@@H](COc2nc(-c3ccc(C#N)c(F)c3)c(-c3ccc4N(C)C(=O)CCc4c3)n3cncc23)C1 |r| Show InChI InChI=1S/C30H29FN6O2/c1-35-11-3-4-19(16-35)17-39-30-26-15-33-18-37(26)29(28(34-30)21-5-6-23(14-32)24(31)13-21)22-7-9-25-20(12-22)8-10-27(38)36(25)2/h5-7,9,12-13,15,18-19H,3-4,8,10-11,16-17H2,1-2H3/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020)
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105576 (US10047086, 102 | US10640503, Example 102 | US9695...) Show SMILES CN1CCC[C@@H](COc2nc(-c3ccc(C#N)c(F)c3)c(-c3ccc4N(C)C(=O)CCc4c3)n3cncc23)C1 |r| Show InChI InChI=1S/C30H29FN6O2/c1-35-11-3-4-19(16-35)17-39-30-26-15-33-18-37(26)29(28(34-30)21-5-6-23(14-32)24(31)13-21)22-7-9-25-20(12-22)8-10-27(38)36(25)2/h5-7,9,12-13,15,18-19H,3-4,8,10-11,16-17H2,1-2H3/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10047086 (2018) BindingDB Entry DOI: 10.7270/Q28917W4
					More data for this Ligand-Target Pair