BDBM106179 US8575197, II-092

SMILES: CNC(=O)c1ccccc1C1N(C(=O)c2n[nH]c(C(C)C)c12)c1ccc(cc1)-c1ccsc1

InChI Key: InChIKey=DSCOIBVZANWSKU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 106179   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM106179 (US8575197, II-092) Show SMILES CNC(=O)c1ccccc1C1N(C(=O)c2n[nH]c(C(C)C)c12)c1ccc(cc1)-c1ccsc1 Show InChI InChI=1S/C26H24N4O2S/c1-15(2)22-21-23(29-28-22)26(32)30(18-10-8-16(9-11-18)17-12-13-33-14-17)24(21)19-6-4-5-7-20(19)25(31)27-3/h4-15,24H,1-3H3,(H,27,31)(H,28,29)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. US Patent					Assay Description Inhibition assay using human P2X3 receptor gene (GeneBank accession number Y07683).				US Patent US8575197 (2013) BindingDB Entry DOI: 10.7270/Q2CN72KP
					More data for this Ligand-Target Pair