BDBM106301 US9695175, 17

SMILES: Cn1cc2c(F)c(ccc2n1)C(F)(F)c1nnc2ccc(nn12)-c1ccc(c(F)c1)S(N)(=O)=O

InChI Key: InChIKey=CPZIGGVWIQTJLY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 106301   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (MET) (Homo sapiens (Human))	BDBM106301 (US9695175, 17) Show SMILES Cn1cc2c(F)c(ccc2n1)C(F)(F)c1nnc2ccc(nn12)-c1ccc(c(F)c1)S(N)(=O)=O Show InChI InChI=1S/C20H13F4N7O2S/c1-30-9-11-15(28-30)4-3-12(18(11)22)20(23,24)19-27-26-17-7-5-14(29-31(17)19)10-2-6-16(13(21)8-10)34(25,32)33/h2-9H,1H3,(H2,25,32,33)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	30
CB THERAPEUTICS INC. US Patent					Assay Description Optiplate-384 well plate (PerKinElmer), kinase buffer (50 mM Hepes pH7.5, 25 mM NaCl, 2 mM DTT, 0.01% Tween 20, 5 mM Mg2+, 0.5 mM Mn2+), c-Met kinase...				US Patent US9695175 (2017) BindingDB Entry DOI: 10.7270/Q28W3BGM
					More data for this Ligand-Target Pair