BDBM106341 US8575197, II-254

SMILES: COc1ccccc1C1N(C(=O)c2n[nH]c(c12)C(C)(C)C)c1ccc(nc1)-c1ccsc1

InChI Key: InChIKey=OIYJBJCEAHVBNG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 106341   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM106341 (US8575197, II-254) Show SMILES COc1ccccc1C1N(C(=O)c2n[nH]c(c12)C(C)(C)C)c1ccc(nc1)-c1ccsc1 Show InChI InChI=1S/C25H24N4O2S/c1-25(2,3)23-20-21(27-28-23)24(30)29(22(20)17-7-5-6-8-19(17)31-4)16-9-10-18(26-13-16)15-11-12-32-14-15/h5-14,22H,1-4H3,(H,27,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. US Patent					Assay Description Inhibition assay using human P2X3 receptor gene (GeneBank accession number Y07683).				US Patent US8575197 (2013) BindingDB Entry DOI: 10.7270/Q2CN72KP
					More data for this Ligand-Target Pair