BDBM106630 US9695175, 37

SMILES: Cn1cc(cn1)-c1ccc2nnc(n2n1)C(F)(F)c1cc2cn(C)nc2cc1F

InChI Key: InChIKey=UDHDJOVGBKPBQS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 106630   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (MET) (Homo sapiens (Human))	BDBM106630 (US9695175, 37) Show SMILES Cn1cc(cn1)-c1ccc2nnc(n2n1)C(F)(F)c1cc2cn(C)nc2cc1F Show InChI InChI=1S/C18H13F3N8/c1-27-9-11(7-22-27)14-3-4-16-23-24-17(29(16)26-14)18(20,21)12-5-10-8-28(2)25-15(10)6-13(12)19/h3-9H,1-2H3	PDB GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	30
CB THERAPEUTICS INC. US Patent					Assay Description Optiplate-384 well plate (PerKinElmer), kinase buffer (50 mM Hepes pH7.5, 25 mM NaCl, 2 mM DTT, 0.01% Tween 20, 5 mM Mg2+, 0.5 mM Mn2+), c-Met kinase...				US Patent US9695175 (2017) BindingDB Entry DOI: 10.7270/Q28W3BGM
					More data for this Ligand-Target Pair