BDBM106703 US8586620, 15
SMILES: CN(C)CCCc1c[nH]c2ccc(cc12)N=C(N)c1cccs1
InChI Key: InChIKey=SLZDCHGYGQWGAB-UHFFFAOYSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nitric oxide synthase, brain (Homo sapiens (Human)) | BDBM106703 (US8586620, 15) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
NeurAxon, Inc. US Patent | Assay Description Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS). | US Patent US8586620 (2013) BindingDB Entry DOI: 10.7270/Q2348J0K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine 1D receptor (5HT1D) (Bos taurus (Bovine)) | BDBM106703 (US8586620, 15) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 870 | n/a | n/a | n/a | n/a | n/a | n/a |
NeurAxon, Inc. US Patent | Assay Description 5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc... | US Patent US8586620 (2013) BindingDB Entry DOI: 10.7270/Q2348J0K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, inducible (Homo sapiens (Human)) | BDBM106703 (US8586620, 15) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NeurAxon, Inc. US Patent | Assay Description Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS). | US Patent US8586620 (2013) BindingDB Entry DOI: 10.7270/Q2348J0K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, endothelial (Homo sapiens (Human)) | BDBM106703 (US8586620, 15) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NeurAxon, Inc. US Patent | Assay Description Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS). | US Patent US8586620 (2013) BindingDB Entry DOI: 10.7270/Q2348J0K | |||||||||||
More data for this Ligand-Target Pair |