BDBM106797 (5Z)‐5‐({3‐[(3,4‐ dichlorophenyl)methoxy]phenyl}methylidene)imidazolidine‐ 2,4‐dione (comp#i)

SMILES: Clc1ccc(COc2cccc(\C=C3/NC(=O)NC3=O)c2)cc1Cl

InChI Key: InChIKey=CAMINEJMWHDHEJ-NVNXTCNLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 106797   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM106797 ((5Z)‐5‐({3‐[(3,4‐ dichloro...) Show SMILES Clc1ccc(COc2cccc(\C=C3/NC(=O)NC3=O)c2)cc1Cl Show InChI InChI=1S/C17H12Cl2N2O3/c18-13-5-4-11(7-14(13)19)9-24-12-3-1-2-10(6-12)8-15-16(22)21-17(23)20-15/h1-8H,9H2,(H2,20,21,22,23)/b15-8-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.36E+4	n/a	n/a	n/a	n/a	6.0	37
Tianjin Medical University					Assay Description The enzyme activity was measured using p-nitrophenyl phosphate (pNPP) as substrate in a 96-well plate and by detecting the absorbance at 405 nm for t...				Chem Biol Drug Des 82: 595-602 (2013) Article DOI: 10.1111/cbdd.12189 BindingDB Entry DOI: 10.7270/Q2K64GQP
					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM106797 ((5Z)‐5‐({3‐[(3,4‐ dichloro...) Show SMILES Clc1ccc(COc2cccc(\C=C3/NC(=O)NC3=O)c2)cc1Cl Show InChI InChI=1S/C17H12Cl2N2O3/c18-13-5-4-11(7-14(13)19)9-24-12-3-1-2-10(6-12)8-15-16(22)21-17(23)20-15/h1-8H,9H2,(H2,20,21,22,23)/b15-8-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	6.0	37
Tianjin Medical University					Assay Description The enzyme activity was measured using p-nitrophenyl phosphate (pNPP) as substrate in a 96-well plate and by detecting the absorbance at 405 nm for t...				Chem Biol Drug Des 82: 595-602 (2013) Article DOI: 10.1111/cbdd.12189 BindingDB Entry DOI: 10.7270/Q2K64GQP
					More data for this Ligand-Target Pair