BDBM106989 US8592579, 47
SMILES: N[C@@H]1CCCN(C1)C(=O)[C@@H]1CCCN1c1nc(Nc2cc([nH]n2)C2CC2)c2cccn2n1
InChI Key: InChIKey=BHFXUUJDRRVKNN-QAPCUYQASA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Insulin-like growth factor I receptor (Homo sapiens (Human)) | BDBM106989 (US8592579, 47) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 361 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Kinase assay using IGF1-receptor. | US Patent US8592579 (2013) BindingDB Entry DOI: 10.7270/Q2SQ8Z12 | |||||||||||
More data for this Ligand-Target Pair |