BDBM107002 US8592579, 107

SMILES: C[C@]1(CCCN1c1nc(Nc2cc(n[nH]2)C2CC2)c2cccn2n1)C(=O)Nc1ncc(Cl)s1

InChI Key: InChIKey=QWYVEQOENADKMY-NRFANRHFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107002   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM107002 (US8592579, 107) Show SMILES C[C@]1(CCCN1c1nc(Nc2cc(n[nH]2)C2CC2)c2cccn2n1)C(=O)Nc1ncc(Cl)s1 |r| Show InChI InChI=1S/C21H22ClN9OS/c1-21(18(32)26-20-23-11-15(22)33-20)7-3-8-30(21)19-25-17(14-4-2-9-31(14)29-19)24-16-10-13(27-28-16)12-5-6-12/h2,4,9-12H,3,5-8H2,1H3,(H,23,26,32)(H2,24,25,27,28,29)/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Kinase assay using IGF1-receptor.				US Patent US8592579 (2013) BindingDB Entry DOI: 10.7270/Q2SQ8Z12
					More data for this Ligand-Target Pair